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dc.contributor.authorChalkias, Athanasios
dc.contributor.authorKuzovlev, Artem
dc.contributor.authorNoto, Antonio
dc.contributor.authord’Aloja, Ernesto
dc.contributor.authorXanthos, Theodoros
dc.creatorChalkias, Athanasios
dc.date.accessioned2018-10-03T09:24:59Z
dc.date.available2018-10-03T09:24:59Z
dc.date.issued2015-12-01
dc.identifierDOI:10.1016/j.ajem.2015.09.006
dc.identifier.issn07356757
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0735675715007822
dc.identifier.urihttps://repo.euc.ac.cy/handle/123456789/342
dc.description.abstractCytochrome c, an electron carrier that normally resides in the mitochondrial intermembrane space, may translocate to the cytosol under ischemic and hypoxic conditions and contribute to mitochondrial permeability transition pore opening. In addition, reperfusion of brain tissue following ischemia initiates a cell death cascade that includes cytochrome c–mediated induction of apoptosis. Further studies are needed to determine the contribution of cytochrome c in the regulation of cell death, as well as its value as an in vivo prognostic marker after cardiac arrest and resuscitation.
dc.relation.ispartofThe American Journal of Emergency Medicine
dc.titleIdentifying the role of cytochrome c in post-resuscitation pathophysiology
dc.typeReview
dc.rights.licenseCopyright © 2015 Elsevier Inc. All rights reserved.
elsevier.identifier.doi10.1016/j.ajem.2015.09.006
elsevier.identifier.eid1-s2.0-S0735675715007822
elsevier.identifier.piiS0735-6757(15)00782-2
elsevier.identifier.scopusid84950280057
elsevier.identifier.pubmedid26494628
elsevier.volume33
elsevier.issue.identifier12
elsevier.coverdate2015-12-01
elsevier.coverdisplaydateDecember 2015
elsevier.startingpage1826
elsevier.endingpage1830
elsevier.openaccess0
elsevier.openaccessarticlefalse
elsevier.openarchivearticlefalse
elsevier.teaserCytochrome c, an electron carrier that normally resides in the mitochondrial intermembrane space, may translocate to the cytosol under ischemic and hypoxic conditions and contribute to mitochondrial...
elsevier.aggregationtypeJournal


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