Lymphocutaneous sporotrichosis: First proven case in Greece and review of the literature
Rigopoulos, Dimitrios G.
Petrikkos, Georgios L.
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Sporotrichosis is a subcutaneous mycosis caused by several dimorphic species of the genus Sporothrix and is rarely encountered in Europe. A case of heterochthonous lymphocutaneous sporotrichosis by S. schenckii in a 22-year-old male patient in Greece is reported. The patient presented with ulcerated lesions in the right lateral region of the neck with regional erythematous nodules along the path of the lymphatic drainage. The infection was acquired during a visit to Colombia. Diagnosis was made by cultures of skin scrapings and tissue at 30°C, which resulted in growth of a filamentous fungus with the macro- and microscopical characteristics of Sporothrix spp. The identification was confirmed after growth of the fungus at 37°C in the form of yeasts. Molecular analysis confirmed relatedness of the involved strain with strains from Latin America. The patient was successfully treated with itraconazole 200 mg per os daily for 4 months. To our knowledge this is the first report of sporotrichosis in Greece since 1969 and the first molecularly documented sporotrichosis case in this country. In light of the latest developments on molecular epidemiology of the Sporothrix species complex, a review of the literature on this disease is also provided.