Recent Submissions

  • Epigenetic dysregulation of HTR2A in the brain of patients with schizophrenia and bipolar disorder 

    Abdolmaleky, Hamid Mostafavi; Yaqubi, Sahab; Papageorgis, Panagiotis; Lambert, Arthur W.; Ozturk, Sait; Sivaraman, Vadivelu; Thiagalingam, Sam (2011-07-01)
    ntroduction: HTR2A gene has been the subject of numerous studies in psychiatric genetics because LSD, which resembles serotonin causes psychosis and atypical antipsychotic drugs target the HTR2A receptor. However, evidence ...
  • Cancer metastasis 

    Ozturk, Sait; Lambert, Arthur W.; Wong, Chen Khuan; Papageorgis, Panagiotis; Thiagalingam, Sam (2015-01-01)
    Metastasis is the cause of almost all cancer-related deaths. It is an extremely complex, multistep process defined as the spreading of cancer cells from their primary site to distant tissues. Once metastasis occurs it ...
  • Breast cancer 

    Lambert, Arthur W.; Ozturk, Sait; Wong, Chen Khuan; Papageorgis, Panagiotis; Thiagalingam, Sam (2015-01-01)
    The notion that breast cancer is not a single disease but many – that there is considerable heterogeneity among different tumors – is not new, having been observed by physicians for decades. But with the advent of powerful ...
  • TGFβ and BMP signaling in cancer 

    Papageorgis, Panagiotis; Lambert, Arthur W.; Ozturk, Sait; Thiagalingam, Sam (2015-01-01)
    Cancer progression is modulated by aberrant expression and secretion of cytokines at various stages. TGFβ and BMP belong to a superfamily of around 40 secreted cytokines that regulate a plethora of biological responses in ...
  • Multiscale modelling of solid tumour growth: the effect of collagen micromechanics 

    Wijeratne, Peter A.; Vavourakis, Vasileios; Hipwell, John H.; Voutouri, Chrysovalantis; Papageorgis, Panagiotis; Stylianopoulos, Triantafyllos; Evans, Andrew T.; Hawkes, David J. (2016-10-01)
    Here we introduce a model of solid tumour growth coupled with a multiscale biomechanical description of the tumour microenvironment, which facilitates the explicit simulation of fibre–fibre and tumour–fibre interactions. ...
  • Nanoparticles for Diagnosis and/or Treatment of Alzheimer's Disease 

    Antimisiaris, Sophia G.; Mourtas, Spyridon; Markoutsa, Eleni; Skouras, Athanasios; Papadia, Konstantina (2014-05-19)
    Recent attempts to develop nanoparticulate systems for diagnosis and/or therapy of neurodegenerative diseases, with main focus on Alzheimer's Disease (AD) are presented. Since the main obstacle to treat brain-located ...
  • Exploring the nano-surface of collagenous and other fibrotic tissues with AFM 

    Stylianou, Andreas; Gkretsi, Vasiliki; Patrickios, Costas S.; Stylianopoulos, Triantafyllos (2017-01-01)
    Atomic force microscope (AFM) is a powerful and invaluable tool for imaging and probing the mechanical properties of biological samples at the nanometric scale. The importance of nano-scale characterization and nanomechanics ...
  • Socio-economic inequality in health: Individual- and area- level measures of socio-economic position 

    Middleton, Nicos; Ellina, Panayiota; Zannoupas, George; Lamnisos, Demetris; Kouta, Christiana (2018-03-22)
  • Algorithmic Game Theory and Applications 

    Mavronicolas, Marios; Lesta, Vicky Papadopoulou; Spirakis, Paul G. (2007-03-01)
    Methods from game theory and mechanism design have been proven to be a powerful mathematical tool in order to understand, control, and efficiently design dynamic, complex networks, such as the Internet. Game theory provides ...
  • Dynamic cloud resource migration for efficient 3D video processing in mobile computing environments 

    Mavromoustakis, Constandinos X.; Mousicou, Paraskevi; Papanikolaou, Katerina; Mastorakis, George; Bourdena, Athina; Pallis, Evangelos M. (2015-01-01)
    This chapter presents a Efficient 3D Video Processing…?>dynamic cloud computing scheme for efficient resource migration and 3D media content processing in mobile computing environments. It elaborates on location and capacity ...
  • Systems modeling of proliferation mechanisms in childhood Acute Lymphoblastic Leukemia 

    Lambrou, George I.; Zaravinos, Apostolos; Adamaki, Maria; Vlahopoulos, Spiros (2012-12-01)
    cute Lymphoblastic Leukemia (ALL) is the most common neoplasm in children, but the mechanisms underlying leukemogenesis are poorly understood, despite the existence of several theories regarding the mechanics of leukemic ...
  • Human Papilloma Virus (HPV) 

    Zaravinos, Apostolos; Mammas, Ioannis N.; Sourvinos, George; Spandidos, Demetrios A. (2016-04-19)
  • Mobile cloud resource management 

    Katzis, Konstantinos (2015-03-31)
    Providing mobile cloud services requires seamless integration between various platforms to offer mobile users optimum performance. To achieve this, many fundamental problems such as bandwidth availability and reliability, ...
  • Mobile cloud resource management 

    Katzis, Konstantinos (2015-09-30)
    Providing mobile cloud services requires seamless integration between various platforms to offer mobile users optimum performance. To achieve this, many fundamental problems such as bandwidth availability and reliability, ...
  • Mobile cloud resource management 

    Katzis, Konstantinos (2015-11-09)
    Providing mobile cloud services requires seamless integration between various platforms to offer mobile users optimum performance. To achieve this, many fundamental problems such as bandwidth availability and reliability, ...
  • Challenges implementing internet of things (IoT) using cognitive radio capabilities in 5G mobile networks 

    Katzis, Konstantinos; Ahmadi, Hamed Reza (2016-01-01)
    This chapter aims at identifying the main design and operation constraints, that smart environments are expected to experience within a 5G wireless/mobile network and how these constraints can be addressed using cognitive ...
  • Design of scheduling algorithms: Applications 

    Riezebos, Jan; Hoc, Jean Michel; Mebarki, Nasser; Dimopoulos, Christos; Van Wezel, Wout M.C.; Pinot, Guillaume (2011-12-01)
    This chapter discusses the insights developed for designing scheduling algorithms according to three design projects where algorithms have been developed. The choice of applications covers a broad spectrum. The methods ...
  • Design of scheduling algorithms 

    Riezebos, Jan; Hoc, Jean Michel; Mebarki, Nasser; Dimopoulos, Christos; Van Wezel, Wout M.C.; Pinot, Guillaume (2011-12-01)
    The accomplishment of a manufacturing company's objectives is strongly connected to the efficient solution of scheduling problems that are faced in the production environment. Numerous methods for the solution of these ...
  • A comparative investigation of scatter correction in 3D PET 

    Polycarpou, Irene; Marsden, Paul K.; Tsoumpas, Charalampos (2011-01-01)
    In 3D PET scatter degrades image quality and quantification. The currently most popular scatter estimation method is the single scatter simulation (SSS) which accommodates for multiple scattering by scaling the single ...
  • Optimisation of preparedness and response of health services in major crises using the IMPRESS platform 

    Dimopoulos, Christos; Dobrinkova, Nina; Finnie, Thomas; Thompson, James; Hall, Ian; Boustras, Georgios; Danidou, Yianna; Efstathiou, Nectarios; Psaroudakis, Chrysostomos; Koutras, Nikolaos; Eftichidis, George; Gkotsis, Ilias; Heckel, Marcel; Olunczek, Andrej; Hedel, Ralf; Kostaridis, Antonis; Moutzouris, Marios; Panunzi, Simona; Seynaeve, Geert; Tsekeridou, Sofia; Vergeti, Danae (2019-01-01)
    We present the IMPRESS software system; a tool that can support the first responders in cases of disaster management and resources allocation and the optimization of response to large-scale emergencies. This is a multi-level ...