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N-acetylcysteine supplementation increases exercise performance and reduces oxidative stress only in individuals with low levels of glutathione
(2018-02-01)
Most of the evidence indicates that chronic antioxidant supplementation induces negative effects in healthy individuals. However, it is currently unknown whether specific redox deficiencies exist and whether targeted ...
Nicotinamide riboside supplementation dysregulates redox and energy metabolism in rats: Implications for exercise performance
(2018-10-01)
New Findings: What is the central question of this study? The aim was to investigate the potential metabolic and redox mechanisms that impaired exercise performance after 21 days of supplementation with 300 mg (kg body ...
Adaptations to endurance training depend on exercise-induced oxidative stress: exploiting redox interindividual variability
(2018-02-01)
Aim: The aim of this study was to reveal the role of reactive oxygen and nitrogen species (RONS) in exercise adaptations under physiological in vivo conditions and without the interference from other exogenous redox agents ...
Antioxidants in Personalized Nutrition and Exercise
(2018-11-01)
The present review highlights the idea that antioxidant supplementation can be optimized when tailored to the precise antioxidant status of each individual. A novel methodologic approach involving personalized nutrition, ...
Spectrophotometric assays for measuring redox biomarkers in blood and tissues: the NADPH network
(2018-01-01)
Nicotinamide adenine dinucleotide (NAD+/NADH) along with its phosphorylated form (NADP+/NADPH) are two molecules ubiquitously present in all organisms, and they play key roles as cofactors in fundamental catabolic and ...
A novel swimming performance test in rats
(2018-01-01)
Swimming is an advantageous exercise modality since it induces limited muscle damage. Performance is a crucial endpoint measurement of physiological relevance in exercise physiology and clinical settings alike. To our ...
Administration of exercise-conditioned plasma alters muscle catalase kinetics in rat: An argument for in vivo-like Km instead of in vitro-like Vmax
(2018-05-01)
Maximal velocity (Vmax) is a well established biomarker for the assessment of tissue redox status. There is scarce evidence, though, that it does not probably reflect sufficiently in vivo tissue redox profile. Instead, the ...