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Systemic redox biomarkers suggest non-redox mediated processes in the prevention of bed rest-induced muscle atrophy after exercise training: The Cologne RSL study
(2020-03-01)
It has been previously reported that eccentric-biased exercise training prevents the decreases in lean body mass after 60 days of head tilt down bed rest (“Cologne RSL Study”). The aim of the present study, as a part of ...
N-acetylcysteine supplementation increases exercise performance and reduces oxidative stress only in individuals with low levels of glutathione
(2018-02-01)
Most of the evidence indicates that chronic antioxidant supplementation induces negative effects in healthy individuals. However, it is currently unknown whether specific redox deficiencies exist and whether targeted ...
Going retro: Oxidative stress biomarkers in modern redox biology
(2016-09-01)
The field of redox biology is inherently intertwined with oxidative stress biomarkers. Oxidative stress biomarkers have been utilized for many different objectives. Our analysis indicates that oxidative stress biomarkers ...
Principles for integrating reactive species into in vivo biological processes: Examples from exercise physiology
(2016-04-01)
The equivocal role of reactive species and redox signaling in exercise responses and adaptations is an example clearly showing the inadequacy of current redox biology research to shed light on fundamental biological processes ...
Reductive stress after exercise: The issue of redox individuality
(2014-01-01)
Exercise has been consistently used as an oxidant stimulus in redox biology studies. However, previous studies have focused on group differences and did not examine individual differences. As a result, it remains untested ...
Experimental verification of regression to the mean in redox biology: differential responses to exercise
(2016-11-30)
An important methodological threat when selecting individuals based on initial values for a given trait is the “regression to the mean” artifact. This artifact appears when a group with an extreme mean value during a first ...
Nicotinamide riboside supplementation dysregulates redox and energy metabolism in rats: Implications for exercise performance
(2018-10-01)
New Findings: What is the central question of this study? The aim was to investigate the potential metabolic and redox mechanisms that impaired exercise performance after 21 days of supplementation with 300 mg (kg body ...
Muscle damage and inflammation after eccentric exercise: Can the repeated bout effect be removed?
(2015-01-01)
The current consensus in exercise physiology is that the repeated bout effect always appears after few eccentric exercise sessions. This is the first attempt to challenge this tenet, by exploiting specificity in muscle ...