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Genetic variability of the distal promoter of the ST2 gene is associated with angiographic severity of coronary artery disease
(2010-10-01)
Genetic polymorphy of the distal promoter region of the ST2 gene influences transcriptional activity and susceptibility to atopic dermatitis and asthma. Based on the inflammatory background of atherosclerosis we hypothesized ...
Viral DNA detection and RAS mutations in actinic keratosis and nonmelanoma skin cancers
(2010-02-01)
Background Actinic keratosis (AK) is a well-established precancerous skin lesion that has the potential to progress to squamous cell carcinoma (SCC). Basal cell carcinoma (BCC) is a locally aggressive slowly growing tumour ...
Transcriptional regulation of TIMPs in ascending aorta aneurysms
(2010-11-01)
he events that result in the establishment and progression of aortic aneurysms are complex and multifactorial. However, degradation of the extracellular matrix (ECM) of aortic tunica media appears to be a consistent ...
Growth factor expression in ophthalmic pterygia and normal conjunctiva
(2010-03-12)
The expression of growth factors in ophthalmic pterygium and phenotypically normal conjunctiva was examined and correlated with the clinical findings. Fifteen specimens of ophthalmic pterygia and 8 specimens of phenotypically ...
Yin yang 1 expression in human tumors
(2010-02-01)
The Yin Yang 1 (YY1) transcription factor has been identified to target a plethora of potential target genes, the products of which are important for proliferation and differentiation. The mechanisms of YY1 action are ...