Now showing items 1-3 of 3
Cholecystokinin-octapeptide stimulates hypothalamic- pituitary-adrenal function in rats: Role of corticotropin-releasing hormone
Peripherally-administered cholecystokinin (CCK) is a profound suppressor of food intake, can promote anxiety, and causes the acute release of ACTH into plasma. Centrally administered corticotropin-releasing hormone (CRH), ...
Interactions between tumor necrosis factor-α, hypothalamic corticotropin-releasing hormone, and adrenocorticotropin secretion in the rat
We studied the effects of tumor necrosis factor-α (TNFα), a macrophage-derived pleiotropic cytokine produced during the inflammatory/immune response, on the function of the hypothalamic-pituitary-adrenal (HPA) axis of the ...
Effects of peripheral benzodiazepine receptor ligands on hypothalamic-pituitary-adrenal axis function in the rat
High concentrations of the 'peripheral' benzodiazepine (pBZD) binding site ('receptor') have been described in the hypothalamus, the pituitary and the adrenal glands. This study was undertaken to examine the effects of ...