Now showing items 1-9 of 9

    • Adaptations to endurance training depend on exercise-induced oxidative stress: exploiting redox interindividual variability 

      Margaritelis, Nikos V.; Theodorou, Anastasios A.; Paschalis, Vassilis; Veskoukis, Aristidis S.; Dipla, K.; Zafeiridis, A.; Panayiotou, George; Vrabas, Ioannis S.; Kyparos, Antonios; Nikolaidis, Michalis G. (2018-02-01)
      Aim: The aim of this study was to reveal the role of reactive oxygen and nitrogen species (RONS) in exercise adaptations under physiological in vivo conditions and without the interference from other exogenous redox agents ...
    • Aging is not a barrier to muscle and redox adaptations: Applying the repeated eccentric exercise model 

      Nikolaidis, Michalis G.; Kyparos, Antonios; Spanou, Chrysoula I.; Paschalis, Vassilis; Theodorou, Anastasios A.; Panayiotou, George; Grivas, Gerasimos V.; Zafeiridis, A.; Dipla, K.; Vrabas, Ioannis S. (2013-08-01)
      Despite the progress of analytic techniques and the refinement of study designs, striking disagreement exists among studies regarding the influence of exercise on muscle function and redox homeostasis in the elderly. The ...
    • Blood reflects tissue oxidative stress: A systematic review 

      Margaritelis, Nikos V.; Veskoukis, Aristidis S.; Paschalis, Vassilis; Vrabas, Ioannis S.; Dipla, K.; Zafeiridis, A.; Kyparos, Antonios; Nikolaidis, Michalis G. (2015-01-01)
      We examined whether the levels of oxidative stress biomarkers measured in blood reflect the tissue redox status. Data from studies that measured redox biomarkers in blood, heart, liver, kidney and skeletal muscle were ...
    • Exercise as a model to study redox homeostasis in blood: The effect of protocol and sampling point 

      Nikolaidis, Michalis G.; Kyparos, Antonios; Dipla, K.; Zafeiridis, A.; Sambanis, Michalis; Grivas, Gerasimos V.; Paschalis, Vassilis; Theodorou, Anastasios A.; Papadopoulos, Stavros; Spanou, Chrysoula I.; Vrabas, Ioannis S. (2012-02-01)
      Twenty males ran either on a level treadmill (nonmuscle-damaging condition) or on a downhill treadmill (muscle-damaging condition). Blood and urine samples were collected before and after exercise (immediately after, 1h, ...
    • Experimental verification of regression to the mean in redox biology: differential responses to exercise 

      Margaritelis, Nikos V.; Theodorou, Anastasios A.; Paschalis, Vassilis; Veskoukis, Aristidis S.; Dipla, K.; Zafeiridis, A.; Panayiotou, George; Vrabas, Ioannis S.; Kyparos, Antonios; Nikolaidis, Michalis G. (2016-11-30)
      An important methodological threat when selecting individuals based on initial values for a given trait is the “regression to the mean” artifact. This artifact appears when a group with an extreme mean value during a first ...
    • Low vitamin C values are linked with decreased physical performance and increased oxidative stress: reversal by vitamin C supplementation 

      Paschalis, Vassilis; Theodorou, Anastasios A.; Kyparos, Antonios; Dipla, K.; Zafeiridis, A.; Panayiotou, George; Vrabas, Ioannis S.; Nikolaidis, Michalis G. (2016-02-01)
      Purpose: It has been suggested that part of the failure of antioxidant supplementation to reduce oxidative stress and promote health is that it has been administered in humans with normal levels of antioxidants. Methods: ...
    • Low-frequency fatigue as an indicator of eccentric exercise-induced muscle injury: The role of vitamin e 

      Kyparos, Antonios; Nikolaidis, Michalis G.; Dipla, K.; Zafeiridis, A.; Paschalis, Vassilis; Grivas, Gerasimos V.; Theodorou, Anastasios A.; Albani, Maria; Matziari, Chrysoula; Vrabas, Ioannis S. (2012-08-17)
      This study investigates whether vitamin E can attenuate eccentric exercise-induced soleus muscle injury as indicated by the amelioration of in situ isometric force decline following a low-frequency fatigue protocol ...
    • Plasma from exercised rats administered to sedentary rats induces systemic and tissue inflammation 

      Goutianos, Georgios; Veskoukis, Aristidis S.; Tzioura, Aikaterini; Paschalis, Vassilis; Margaritelis, Nikos V.; Dipla, K.; Zafeiridis, A.; Vrabas, Ioannis S.; Nikolaidis, Michalis G.; Kyparos, Antonios (2016-12-01)
      Recent studies have consistently supported the active role of blood in mediating biochemical and physiological tissue adaptations. However, no study has investigated the possible contribution of circulating factors in an ...
    • The rat closely mimics oxidative stress and inflammation in humans after exercise but not after exercise combined with vitamin C administration 

      Veskoukis, Aristidis S.; Goutianos, Georgios; Paschalis, Vassilis; Margaritelis, Nikos V.; Tzioura, Aikaterini; Dipla, K.; Zafeiridis, A.; Vrabas, Ioannis S.; Kyparos, Antonios; Nikolaidis, Michalis G. (2016-04-01)
      Purpose: The purpose of the present study was to directly compare oxidative stress and inflammation responses between rats and humans. Methods: We contrasted rat and human oxidative stress and inflammatory responses to ...